Principal Scientist, Immunology
Role summary
Jade Bioscience is seeking a Principal Scientist, Translational Research, to lead immunology-driven research for pipeline programs focused on autoimmune and inflammatory diseases. This remote role involves designing and overseeing mechanism-of-action studies, integrating data to inform clinical development, and identifying new targets and indications. The ideal candidate will have a PhD in Immunology with 8-12+ years of industry experience, deep expertise in immunology and disease biology, and a strong understanding of drug development. Experience with immunological assays and cross-functional collaboration is essential. The role requires strong scientific writing and communication skills, with a track record of publications and presentations.
About Jade Biosciences
Jade Biosciences is a clinical-stage biotechnology company focused on developing best-in-class therapies that address critical unmet needs in autoimmune diseases. Jade’s lead candidate, JADE101, targets the cytokine APRIL, and is currently being evaluated in a Phase 1 clinical trial for the treatment of immunoglobulin A nephropathy. Jade’s pipeline also includes JADE201, an afucosylated anti-BAFF-R monoclonal antibody, as well as JADE301, an undisclosed antibody candidate, both currently in preclinical development. Jade was launched based on assets licensed from Paragon Therapeutics, an antibody discovery engine founded by Fairmount. For more information, visit JadeBiosciences.com and follow the Company on LinkedIn.
Role Overview
The Research and Translational Medicine group at Jade is looking to add a Principal Scientist, Translational Research, to our team. This role will provide scientific leadership across immunology-driven research activities that support Jade’s pipeline programs, including mechanism-of-action studies, disease biology assessment, indication evaluation, and translational strategy. The Principal Scientist will integrate literature, experimental data, and translational insights to strengthen program rationale, inform clinical development, and identify opportunities for pipeline expansion. This is an exciting opportunity to join a growing, highly collaborative biotech team and contribute to the advancement of potentially best-in-class therapies for autoimmune and inflammatory diseases.
This is a fully remote role, preferably based on the U.S. West Coast, with occasional domestic and international travel. The position reports to the Executive Director, Research and Translational Medicine.
Key Responsibilities
Qualifications
Position Location
This is a remote role; periodic travel to team and company events is required.
The anticipated salary range for candidates for this role is $175,000 - $190,000. The final salary offered will depend on several factors, which may include, but not limited to, relevant years of experience, educational background, and geography.
As part of the I-9 verification of authorization to work in the United States, Jade Bioscience participates in E-Verify. To learn more about E-Verify please review this poster.
Jade Biosciences is proud to be an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.
