Principal Scientist, Clinical Pharmacology
Required skills
- clinical pharmacology
- pharmacokinetics
- biomarkers
- clinical development
- biometrics
- regulatory affairs
- model-informed drug development
- MIDD
- population PK/PD
- PK/PD
Nice to have
- antibody-based therapies
- quantitative discipline
Role summary
AbCellera is seeking an experienced Principal Scientist in Clinical Pharmacology to lead the strategy for antibody-based therapies from first-in-human through late-stage development. This role involves applying Model-Informed Drug Development (MIDD) approaches to optimize trial designs, justify doses, and inform development decisions. You will act as the clinical pharmacology voice on cross-functional teams and in interactions with health authorities. The ideal candidate has a PhD or PharmD with 8+ years of experience, expertise in population PK/PD, exposure-response modeling, pharmacometrics tools (NONMEM, Monolix, R), and experience with regulatory submissions. Experience managing CROs and working with biologics is also required. The role offers a competitive salary, equity, bonus, and benefits.
Each of us cares about someone who will need medicines. That’s why our vision is to repeatedly beat the odds to deliver breakthrough medicines to patients who need them. We pursue truth and scientific rigour and have the courage to work at the edge of the unknown.
We are seeking an experienced scientist with expertise in Clinical Pharmacology who can help shape how AbCellera's antibody-based therapies are dosed, studied and developed, from first-in-human through late-stage development. In this role, you will lead the clinical pharmacology strategy for therapeutic programs while working closely with members from our Pharmacokinetics, Biomarkers, Clinical Development, Biometrics and Regulatory Affairs teams. You will apply Model-Informed Drug Development (MIDD) approaches to optimize clinical trial designs, justify dose selections, inform development decisions and mitigate risks across both early and late-stage development, acting as the clinical pharmacology voice on cross-functional program teams and in interactions with health authorities. If you are a clinical pharmacologist who is excited to use modeling and data to guide novel antibody therapies toward patients, we’d love to hear from you.
How you might spend your days
We’d love to hear from you if
What we offer
AbCellera’s hiring range for this role is CAD $170,000 - $200,000 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, an annual bonus dependent on individual and company performance, and a 6% (non-match) RRSP contribution.
You will have a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits. Scientific and technical mentorship are a priority. And you’ll find a strong sense of community and connections across AbCellera through our work, clubs, and socials.
About AbCellera
Creating medicines is the most important work we can do.
We are a clinical-stage biotechnology company focused on discovering and developing antibody-based medicines in the areas of endocrinology, women’s health, immunology, and oncology. We have built a platform for advancing antibody drug programs from target to clinic, and we are using it to build our internal pipeline. Today, our pipeline includes two drug candidates in clinical development, two preclinical development candidates (DCs) in Investigational New Drug (IND)-enabling activities, and more than 20 active discovery programs across multiple modalities and indications.
We believe that when tenacious people share a vision and work together, they can truly have a positive impact. That’s why we hire for character and intelligence, not just for CVs or experience.
We look for people with drive and energy. People we trust. People who need to know their days are being well spent. That their work really matters. In the end, our success will be measured by the impact of our medicines.
To apply
Please submit your application through our website and refer to Job ID 23427 in your cover letter. We receive a large volume of applications and are only able to contact those who are selected for an interview. All communication from our Talent Discovery team will come from an @abcellera.com email address.
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