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Life Sciences, Diagnostics, Environmental & Applied Solutions, Dental

Principal Cybersecurity Architect

Irvine, CAOnsiteFull TimePrincipal$170,000–$210,000 /yrPosted 1 month agoVisa sponsorship available

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Required skills

  • secure-by-design
  • software platforms
  • software development lifecycle
  • patient safety
  • product integrity
  • regulatory compliance
  • cybersecurity risk
  • development velocity
  • B.S. Degree
  • Cybersecurity

Nice to have

  • regulated industries
  • medical devices
  • healthcare technology
  • safety-critical environments
  • NIST
  • ISO 27001

Role summary

Masimo, a global medical technology company, seeks a Principal Cybersecurity Architect to embed secure-by-design principles across its software platforms. This senior technical role partners with engineering, quality, regulatory, and product teams to integrate cybersecurity into architecture and the SDLC. Responsibilities include defining secure architecture strategies, strengthening software resilience, and mentoring teams on secure development. The position requires a B.S. degree and 15+ years of experience in software architecture, cybersecurity engineering, or product security, with deep expertise in secure design and application security. Experience in regulated industries and familiarity with frameworks like NIST and OWASP are preferred. The role is based in Irvine, CA, and is an on-site, full-time position with an annual salary range of $170,000 - $210,000.

Bring more to life.

 

Are you ready to accelerate your potential and make a real difference within life sciences, diagnostics and biotechnology?

At Masimo, one of Danaher’s 15+ operating companies, our work saves lives—and we’re all united by a shared commitment to innovate for tangible impact. 

You’ll thrive in a culture of belonging where you and your unique viewpoint matter. And by harnessing Danaher’s system of continuous improvement, you help turn ideas into impact – innovating at the speed of life.

Masimo is a global medical technology company that develops and produces a wide array of industry-leading monitoring technologies, including non-invasive measurements, sensors, patient monitors, and automation and connectivity solutions. Our mission is, Masimo innovations empower clinicians to transform patient care. When you join our team, you’ll be part of a culture that’s driven by passion, challenging the status quo, and making an impact in the lives of others.

 

Learn about the Danaher Business System which makes everything possible.

The Principal Cybersecurity Architect serves as a senior technical authority responsible for embedding secure-by-design principles across Masimo’s software platforms. This role partners closely with software, algorithm, quality, regulatory, and product teams to ensure cybersecurity considerations are integrated throughout system architecture and the software development lifecycle.


This role focuses on advancing product security strategy, strengthening software resilience, and enabling engineering teams to deliver innovative, secure solutions that support patient safety, product integrity, and regulatory compliance. The Principal Cybersecurity Architect provides deep technical expertise, architectural guidance, and cross-functional leadership to proactively reduce cybersecurity risk while maintaining development velocity.


The position reports to the SVP, Software Engineering and is part of the Software Engineering department located in Irvine, CA and will be an on-site role.


In This Role, You Will Have The Opportunity To:


  • Define and drive secure architecture strategies across cloud, desktop, mobile, and embedded software platforms.
  • Embed secure-by-design principles into engineering processes, including threat modeling, architecture reviews, and risk assessments.
  • Partner with software engineering leaders to integrate cybersecurity practices into CI/CD pipelines and DevSecOps workflows.
  • Establish scalable product security standards, reference architectures, and engineering guidelines aligned to industry frameworks.
  • Mentor engineering teams and architects on secure development practices and emerging cybersecurity trends.

The Essential Requirements Of The Job Include:

 

  • B.S. Degree in Computer Science, Cybersecurity, Software Engineering, or a related technical field.
  • 15+ yrs of extensive experience in software architecture, cybersecurity engineering, or product security within complex technical environments.
  • Deep expertise in secure software design, application security, and modern software development practices.
  • Proven ability to influence engineering organizations through technical leadership rather than direct people management.
  • Strong experience with threat modeling, vulnerability assessment, and risk-based security decision-making.
  • Experience integrating cybersecurity into the full software development lifecycle across multiple platforms.
  • Ability to communicate complex technical concepts clearly to engineering and cross-functional stakeholders.

It would be a plus if you also possess previous experience in:

 

  • Experience supporting cybersecurity in regulated industries such as medical devices, healthcare technology, or other safety-critical environments.
  • Familiarity with industry frameworks such as NIST, ISO 27001, OWASP, or similar cybersecurity standards.
  • Experience with cloud-native architectures, embedded systems, or hybrid software ecosystems.
  • Relevant certifications such as CISSP, CSSLP, or equivalent.
  • Demonstrated track record influencing architecture strategy at an enterprise or multi-product level.

Masimo, a Danaher operating company, offers a broad array of comprehensive, competitive benefit programs that add value to our lives. Whether it’s a health care program or paid time off, our programs contribute to life beyond the job. Check out our benefits at Danaher Benefits Info.


The annual salary range OR the hourly range for this role is $170,000 - $210,000. This is the range that we in good faith believe is the range of possible compensation for this role at the time of this posting. This range may be modified in the future. 


This job is also eligible for bonus/incentive pay. 


We offer comprehensive package of benefits including paid time off, medical/dental/vision insurance and 401(k) to eligible employees. 


Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole discretion unless and until paid and may be modified at the Company’s sole discretion, consistent with the law. 

Join our winning team today. Together, we’ll accelerate the real-life impact of tomorrow’s science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life.


For more information, visit www.danaher.com.


Danaher Corporation and all Danaher Companies are committed to equal opportunity regardless of race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law.


The U.S. EEO posters are available here.


For candidates who are based outside of New York City or who are applying for roles outside of New York City, for more information about conditions of any job offer please click here.


We comply with federal and state disability laws and make reasonable accommodations for applicants and employees with disabilities. If reasonable accommodation is needed to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please contact:1-202-419-7762 or applyassistance@danaher.com.

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