
Director, Multiomics Bioinformatics
Required skills
- Bioinformatics
- Computational Biology
- Statistics
- Genomics
- multiomics
- single cell
- spatial biology
- proteomics
- epigenomics
- NGS
Role summary
Illumina is seeking a Director, Multiomics Bioinformatics to provide strategic leadership for its multiomics portfolio, including single cell, spatial biology, proteomics, epigenomics, and emerging technologies. This role involves leading a team of bioinformatics scientists and engineers to define and execute informatics strategies for end-to-end customer multiomics workflows. The Director will collaborate with Product Management, Assay Development, Software Engineering, Clinical Development, and Commercial teams to align bioinformatics capabilities with product roadmaps and business objectives. The position requires a PhD in a related scientific discipline with 10+ years of relevant experience, demonstrated leadership in managing bioinformatics organizations and programs, and a track record of delivering customer-facing products. Experience with cloud platforms, AI/ML, and large-scale biological data analysis is essential.
The Director, Bioinformatics will provide strategic leadership for Illumina's multiomics bioinformatics portfolio, spanning single cell, spatial biology, proteomics, epigenomics, and emerging multiomics technologies. Leading a team of bioinformatics scientists and engineers, this leader will define and execute informatics strategies that enable end-to-end customer multiomics workflows. The role will involve partnering closely with Product Management, Assay Development, Software Engineering, Clinical Development, and Commercial organizations to align bioinformatics capabilities with product roadmaps, customer needs, and business objectives.
Responsibilities:
Strategy -- define and drive bioinformatics strategy across Illumina's multiomics portfolio, including single cell, spatial biology, proteomics, epigenomics, and emerging multiomics technologies
Vision -- establish the long-term vision for customer-facing informatics experiences and end-to-end product workflows
Innovation -- drive innovation in analysis methods, AI-enabled workflows, and next-generation multiomics capabilities
Leadership -- lead, develop, and grow a team of bioinformatics scientists and engineers, and lead programs from concept through commercial launch
Partnership -- represent Bioinformatics and partner cross-functionally to develop technology roadmaps and investment priorities
Listed responsibilities are an essential, but not exhaustive list, of the usual duties associated with the position. Changes to individual responsibilities may occur due to business needs.
Requirements:
PhD in Bioinformatics, Computational Biology, Computer Science, Statistics, Genomics, or related scientific discipline, with 10+ years of relevant experience preferred
Demonstrated leadership experience managing complex bioinformatics organizations and programs
Track record of delivering customer-facing software, analytical methods, or informatics products, including support of commercial launches
Experience leading cross-functional product development initiatives
Strong understanding of NGS, genomics, transcriptomics, proteomics, or related multiomics technologies
Experience with cloud-scale informatics platforms, AI/ML technologies, and large-scale biological data analysis
Excellent communication and stakeholder management skills
All listed requirements are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional task and responsibilities.
Experience/Education:
Typically requires a Bachelor’s degree and a minimum of 18 years of related experience, with 10+ years of Management experience.
#LI-ONSITE
The estimated base salary range for the Director, Multiomics Bioinformatics role based in the United States of America is: $205,100 - $307,700. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long‑term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact accommodations@illumina.com. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.
Sample Illumina interview questions
- 1
Create a scalable system for managing versioned data across distributed systems.
system designmedium - 2
Lowest Common Ancestor on an N-ary Tree Find the lowest common ancestor on an N-ary tree. Input: root = [1,null,2,3,4], p = 2, q = 3 Output: 1 Explanation: Both nodes 2 and 3 are direct children of the root node 1, making 1 the lowest common ancestor.
technicalmedium - 3
Vertical Order Traversal Perform a vertical order traversal of a binary tree. Input: root = [1,2,3,4,5,6,7] Output: [[4],[2],[1,5,6],[3],[7]] Explanation: Traverses the tree maintaining column indices, seamlessly grouping nodes that share the exact same vertical alignment.
technicalmedium - 4
Count Anagrammatic Substrings Count the number of anagrammatic substrings from one string present in another. Input: s = "abab", p = "ab" Output: [0, 1, 2] Explanation: The substrings "ab", "ba", and "ab" starting at indices 0, 1, and 2 respectively are all anagrams of the string "ab".
technicalmedium - 5
Sort a String by Frequency Sort a string by the frequency of its characters. Input: s = "cccaaa" Output: "cccaaa" or "aaaccc" Explanation: Both 'c' and 'a' appear three times, so sorting them by descending frequency keeps them grouped equally.
technicalmedium
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