Scientist III - Mass Spec Production (LC-MS/MS)

Performing critical work that impacts our industry and our world’s health while problem solving and innovating in the field – that is what Scientists at KCAS Bio get to do every day. If that gets you excited too, then maybe working as a Scientist at KCAS Bio is the role for you.

When you work as a Scientist III in the Mass Spec Bioanalysis Development group at KCAS, you get to further our mission by leveraging your knowledge in bioanalytical and scientific principles to execute and take ownership of significant aspects of studies, from study setup through reporting, as well as contribute to development activities. You will utilize your strong base in scientific principles/theories to assess data integrity and troubleshoot when necessary.

Our Mass Spec Bioanalysis Development team uses LC-MS/MS (Liquid Chromatography–Tandem Mass Spectrometry) techniques and sophisticated sample preparation methods to meet bioanalytical needs for drug discovery, preclinical, and clinical studies, including the bioanalysis of drugs and metabolites, biomarkers, and active endogenous compounds in biological fluids and tissues.

In this role, we will rely on you to:

Execute and take ownership of key study components including sample preparation, LC-MS/MS analysis, troubleshooting, data analysis, and documentation

Contribute to method development, qualification, and optimization efforts

Troubleshoot complex technical issues and recommend solutions

Analyze and interpret data with minimal oversight

Prepare data summaries and contribute to report generation

Ensure compliance of study activities with pertinent portions of study protocol, SOPs & regulatory requirements

Communicate study progress to senior scientists and management as required

Provide guidance and mentorship to junior scientific staff

Perform all aspects of the job in a way that supports company brand and supports company mission, vision, and values

To qualify specifically for this role, you will have:

Bachelor’s, Master’s, or PhD in Chemistry, Biochemistry or chemical/biochemical engineering, or related field with at least 4–6 years of experience with LC-MS/MS

Strong experience with bioanalytical sample preparation, quantitative LC-MS/MS, and multi-dimensional chromatography

Experience contributing to method development, qualification, and complex troubleshooting

Experience with proteins and peptides as well as small molecule biomarkers is preferred

Experience with reversed phase and HILIC chromatography at analytical flow rates or protein digestions and immunoaffinity enrichments (hybrid LCMS) is a plus

Experience working in a regulated environment (GLP/GxP)

Depending on your background and qualifications, we may consider hiring you for one of three levels of Scientist roles at KCAS Bio. This will be determined during the interview process.
(Please note this is a representative summary of responsibilities, not a comprehensive or exclusive list of the duties to be performed in any position. Employees must follow instructions and perform additional duties as requested.)
WHO YOU AREYou will thrive at KCAS Bio if you enjoy a relational environment, are purpose- and values-driven, embrace constant development and supportive leadership, and enjoy being part of innovative work.
WHAT YOU’LL GETOur benefits include, and extend beyond, the traditional package. At KCAS Bio, you will enjoy company sponsored events like food trucks, family days and spirit days. You will grow in your career with KCAS University. You will be able to connect with like-minded employees to further KCAS Bio's approach to key areas such as wellness, inclusion, and community outreach. You will engage as an owner in our stock ownership program. You will have access to the latest technology. And you will be able to invest in the community with paid time off to volunteer.
Learn more about the Benefits at KCAS Bio 
WHO WE AREWe are a fast-growing contract research organization (CRO) headquartered in Kansas City, pioneering the latest drug development in both human and animal health fields. Demand for our expertise is growing and so is our need for great people to work in nimble, empowered teams committed to one another’s growth. At KCAS Bio, we advance both great science AND great people.
Learn more about what it is like to work at KCAS Bio
KCAS Bio is proud to be an Equal Opportunity Employer. Among other things, we provide equal employment opportunities without regard to race, color, religion, national origin, ancestry, marital status, veteran status, age, disability, pregnancy, genetic information, sex, sexual orientation, gender identity, or any other legally protected category; we recruit qualified candidates without regard to citizenship status based on internal processes that enable us to hire the right candidates consistent with the appropriate U.S. Immigration framework; and (3) we work with and provide reasonable accommodations to individuals with disabilities and for sincerely held religious beliefs, observances, and practices. Anyone who needs reasonable accommodation may send an email to kcasrecruiting@kcasbio.com or call 913-248-3000 (for TTY assistance call 711) and ask for Human Resources. IND123