Biotechnology, Pharmaceuticals, Life Sciences

Senior Director, Outcomes, Value & Access

Watertown, MAOnsiteFull TimeDirector$235,000–$330,000 /yrPosted 2 months agoVisa sponsorship available

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Required skills

health economics
real-world evidence
value communication
payer strategy
medical strategy
patient access
clinical decision-making
product commercialization
HEOR
economic modeling

Nice to have

early-stage products
launch-stage products
specialty immunology
field-based payer medical teams
Global HEOR/HTA
ex-US HEOR/HTA

Role summary

Kymera Therapeutics, a clinical-stage biotechnology company focused on targeted protein degradation (TPD), seeks a Senior Director, Outcomes, Value & Access. This strategic leadership role, reporting to the VP of Medical Affairs, will drive the company's health economics, real-world evidence (RWE), value communication, and payer-relevant medical strategy across the immunology pipeline. The ideal candidate possesses deep immunology expertise (dermatology/respiratory preferred), a proven track record in HEOR and market access, and experience engaging with payer stakeholders. Responsibilities include developing and executing integrated outcomes and access strategies, overseeing HEOR and RWE plans, building payer relationships, and leading a high-performing team to ensure optimized patient access and successful product commercialization in a dynamic biotech environment.

Who we are:

Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn.

How we work:

PIONEER: We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.

COLLABORATE: We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.

BELONG: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.

How you’ll make an impact:

The Senior Director, Outcomes, Value & Access will serve as Kymera’s strategic leader for health economics, real-world evidence (RWE), value communication, and payer-relevant medical strategy across the pipeline. Reporting to the VP of Medical Affairs, this role will shape and execute the company’s integrated outcomes and access strategy to support optimized patient access, informed clinical decision-making, and successful product commercialization. The ideal candidate is an experienced HEOR leader with deep immunology expertise (dermatology and/or respiratory strongly preferred), a proven track record preparing for and supporting launches, and significant experience engaging national and regional payer stakeholders.

Strategic and forward-thinking, with the ability to translate scientific evidence into compelling value narratives.

Highly collaborative, diplomatic, and influential across functions and levels.

Strong communicator with exceptional scientific and business acumen.

Comfort working in a dynamic, rapidly growing biotech setting.

Strategic Leadership & Vision

Lead the development and execution of Kymera’s Medical Outcomes, Value & Access strategy across the immunology portfolio.

Serve as a core member of the Medical Affairs Team, advising on evidence generation, clinical strategy, and payer-relevant insights.

Drive cross-functional alignment on value strategy across Medical Affairs, HEOR, Market Access, Clinical Development, Regulatory, Commercial, and Global teams.

Health Economics & Outcomes Research (HEOR)

Oversee HEOR strategy, including economic modeling, treatment-pattern studies, and comparative-effectiveness analyses.

Guide development and validation of economic models (e.g., budget impact, cost-effectiveness) to support payer decision-making.

Lead creation of AMCP dossiers, value narratives, and scientific payer resources.

Real-World Evidence & Data Generation

Design and oversee RWE plans, including study concept refinement, protocol development, external data partnerships, and post-marketing evidence strategy.

Partner with Clinical Development and Data Science teams to integrate outcomes-focused endpoints into clinical trial design.

Payer & External Stakeholder Engagement

Build and maintain relationships with U.S. payer organizations, HTAs, integrated delivery networks, and employer groups to communicate clinical and economic value.

Lead scientific exchange with medical directors, formulary decision-makers, and population-health leaders.

Conduct advisory boards on HEOR, RWE, and access-related topics.

Cross-Functional Collaboration & Enablement

Provide leadership for value and access–related launch preparation.

Collaborate with Market Access to ensure scientific accuracy and strategic alignment of access resources.

Serve as lead on health technology assessment (HTA) readiness for future ex-US markets, in partnership with global teams.

Support field medical teams with training on HEOR, RWE, and payer communication.

Team Leadership & Development

Build and lead a high-performing Outcomes, Value & Access team, fostering a culture of scientific excellence, collaboration, and accountability.

Manage budgets, timelines, and resource allocation across projects and vendors.

Skills and experience you’ll bring:

Required

Advanced degree: PharmD, PhD, MD, MS/MPH in HEOR, Epidemiology, or related field.

10+ years of experience in Medical Affairs, HEOR, Market Access, or related roles in the biopharmaceutical industry.

Demonstrated leadership in building or expanding HEOR or Medical Value/Access functions.

Strong therapeutic experience in immunology, with dermatology and/or respiratory as a plus.

Proven track record developing payer-focused HEOR strategy, RWE programs, value communication tools, and AMCP dossiers.

Experience engaging directly with national and regional payer decision-makers.

Strong understanding of U.S. healthcare economics, HTA landscapes, and evolving value-based frameworks.

Ability to work collaboratively in a fast-paced, science-driven, cross-functional environment.

Preferred

Experience supporting early-stage to launch-stage products in specialty immunology.

Prior leadership of field-based payer medical teams.

Global or ex-U.S. HEOR/HTA exposure.

Experience in small or mid-size biotech environments.

Equal Employment Opportunity

Kymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.

Compensation

Kymera offers a competitive compensation package that recognizes both results and capabilities through market-based, performance-driven pay.

The anticipated base salary range for this role is $235,000 – $330,000, with eligibility for annual bonus, equity participation, and comprehensive benefits.

Actual salary is based on a holistic evaluation of the specific role/level as well as each candidate’s depth of experience and the capabilities they bring to the position.

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