Wet Lab Staff Scientist

MyOme is a clinical whole genome analysis company helping individuals and families understand their risk for disease. As a leader in polygenic and AI-based integrative risk modeling, we combine genome sequencing with AI-driven analytics and clinical data to deliver a lifetime of clinically meaningful, actionable insights, from proactive risk assessment to rare disease diagnosis. Our laboratory is CLIA-certified and CAP-accredited, and we’re based in Menlo Park, California.

Our team brings together scientists, engineers, clinicians, and professionals across disciplines, united by a shared purpose: making genomic insight a routine part of everyday healthcare. We put patients first and hold ourselves to the scientific and clinical rigor that families and their clinicians depend on.

Joining MyOme means contributing your expertise to work that matters for patients and families. Whether you’re advancing our science and technology, supporting the clinicians and patients we serve, or strengthening our operations, you’ll help turn genomic discoveries into better care.

Position Overview:

MyOme is seeking an experienced and innovative senior wet lab scientist who can both guide development efforts and contribute to our NGS assay development roadmap. This person will initially lead efforts to incorporate RNASeq into MyOme’s clinical testing workflow and evaluate additional new technologies. The ideal candidate has proven experience standing up clinical NGS assays and is able to think critically and creatively to deliver results.

What You'll Do:

Develop a comprehensive project plan for bringing RNASeq in house, covering development milestones, hiring needs, validation strategy, budget, and quality control

Lead the technical development and validation of RNASeq assays, ensuring they meet MyOme's quality and performance standards

Partner with automation engineers to design efficient, scalable wet lab workflows suited for clinical scale throughput and collaborate with clinical lab staff to ensure new assays meet regulatory and clinical laboratory requirements

Work closely with the research bioinformatics team to align wet lab processes with downstream data analysis and pipeline needs

Mentor and guide wet lab scientists, providing technical direction on assay development and validation work

Expand the in house assay portfolio over time by leading evaluation and (if warranted) development efforts for additional assays (e.g. Illumina TruPath, proteomics)

Present project plans, progress, and findings to senior leadership

Guide the publication and presentation plan for assay components as well as IP strategy

What You'll Need:

Advanced degree (PhD) in Molecular Biology, Genomics, Biochemistry, or a related field, or equivalent practical experience

8+ years of wet lab experience, including hands-on work with RNASeq and next generation sequencing technologies. Experience with additional analytes (e.g., proteomics, methylation) is a plus

Experience developing and executing project plans that include technical development, validation, budget, and quality control components

Familiarity with clinical laboratory requirements and standards (e.g., CLIA/CAP) and experience bringing assays to a scalable and clinically ready state

Strong collaboration skills, with experience working across wet lab, bioinformatics, clinical, and engineering teams

Excellent communication skills and ability to articulate scientific and technical concepts to non-experts

Location, Compensation, and Benefits:

Location: Onsite 5 days a week at our Menlo Park, CA laboratory campus

Compensation: Annual salary range is $170,000 - $185,000, commensurate with experience. This role is also eligible for equity.

San Francisco Bay Area pay range$170,000—$185,000 USD

Benefits:

Comprehensive healthcare coverage (Health, Dental, and Vision)

401K

Professional development opportunities

Company-sponsored off-sites and team meals during in-person meetings

Direct access to company leadership and the opportunity for career growth

Equal Employment Opportunity and Reasonable Accommodations

MyOme is an equal opportunity employer. We make employment decisions without regard to race, color, ancestry, national origin, religion, age, sex (including pregnancy, childbirth, breastfeeding, and related medical conditions), gender, gender identity or expression, sexual orientation, marital status, physical or mental disability, medical condition, genetic information, military or veteran status, reproductive health decision-making, or any other characteristic protected by applicable law. MyOme provides reasonable accommodations to qualified applicants with disabilities and as otherwise required by law. To request an accommodation during the application or interview process, please contact hr@myome.com.

Why Work at MyOme?

Join us if you:

Want to make an impact at the intersection of healthcare and technology, changing the way people engage with their health at the genetic level

Enjoy rolling up your sleeves, taking initiative, and being empowered to lead

Value humility, transparency, and collaborative problem-solving

Thrive in fast-moving, dynamic environments with smart, driven teammates

Appreciate competitive compensation, meaningful equity, and excellent benefits

Learn More: myome.com