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Biotechnology, Pharmaceutical, Healthcare, Clinical Research, Data Analytics

Senior Scientist

Houston, TXOnsiteFull TimeSenior$100,600–$151,000 /yrPosted 15 days agoVisa sponsorship available

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Required skills

  • cell biology
  • oncology
  • laboratory experience
  • cell culture
  • manual staining
  • automated protocols
  • Leica Bond autostainer
  • Indica Halo
  • digital pathology software
  • team-oriented environment

Nice to have

  • academic core
  • industry
  • GLP
  • ISO
  • CAP
  • CLIA

Role summary

This Senior Scientist position leads protein expression assay development and execution for tissue and liquid biopsies in a translational research setting. Responsibilities include assay design, validation, sample testing, and improving laboratory procedures and SOPs. The role involves independent experimental design, data analysis, and presentation, as well as training and mentoring junior staff. Effective communication with clients and internal stakeholders, project timeline management, and budget monitoring are key. The position requires a Ph.D. or Master's degree with significant laboratory experience, including cell culture and multiplex immunofluorescence (mIF) assays, and experience with digital pathology software. Experience with GLP/ISO/CAP/CLIA standards and supervising technical personnel is preferred. The role involves occasional extended work hours and physical demands related to laboratory work.

Position Summary:

This position will lead protein expression assays on tissues and liquid biopsies (circulating tumor cells, CTCs). Responsibilities include performing assay design and development, validation, and sample testing in a timely manner. Ensures assays are performed according to SOPs and supports development of new procedures and improvement of existing SOPs. Supervises assigned laboratory staff to ensure efficient organization, quality, development, and execution of project(s). Communicating results effectively to clients and develop lasting relationships to support future work.

Essential functions of the job include but are not limited to:

  • Leads the development and implementation of protein expression services to support the translational research needs of Precision customers
  • Designs and performs experiments independently, and accurately analyzes and presents data
  • Conduct and support GCLP-compliant laboratory activities for sponsor clinical studies, ensuring adherence to study protocols, validated or qualified assay procedures, SOPs, data-integrity requirements, and established timelines while contributing to investigation of deviations and delivery of high-quality study data.
  • Maintains a high-quality output with the ability to build efficiency into improving productivity metrics
  • Coordinates with management to develop project timelines and deliver on these timelines
  • Trains and mentors’ junior staff in cell culture and antibody staining techniques, data analysis, collation, and presentation
  • Assists in establishing and improving all procedures and required SOP documentation
  • Responsible for trouble shooting and correcting scientific issues/problems
  • Responsible for ensuring that all experiments are performed on qualified equipment and that use and maintenance logs are up to date when performing experiments.
  • Maintains and supports safe lab practices and environment
  • Collaborate with other technical teams in resource sharing and providing technical expertise
  • Monitors project related expenses
  • Serves as a scientific resource to external clients and internal stakeholders
  • Assists with writing reports and presentations for clients as appropriate
  • Supervises assigned project related laboratory staff to ensure quality, development, and execution of project(s).
  • Other duties as assigned
  • Qualifications:

    Minimum Required:

  • Ph.D. in cell biology, oncology, or related fields and 6+ years’ relevant laboratory experience OR
  • Master’s Degree and 10+ years’ in an academic core or industry is required
  • Other Required:

  • Experience in cell culture
  • Experience with manual staining and automated protocols (e.g. use of the Leica Bond autostainer) for multiplex Immunofluorescence (mIF) assays
  • Experience with Indica Halo or other digital pathology software
  • Ability to prioritize tasks and function in a team-oriented environment
  • Excellent communication, interpersonal, and organizational skills
  • Must have the ability to organize and analyze data, as well as prepare reports
  • Excellent use of judgment and discretion required
  • Extended work hours may be occasionally necessary in order to meet business demands
  • Ability to lift and carry between 1-15 lbs.; Ability to lift up to 50 lbs. overhead with assistance; frequently required to sit, grasp, and use right/left finger dexterity; May be exposed to a cold freezer environment (Freezer temperatures range between -20ºC -196ºC)
  • Must be able to read, write, speak fluently and comprehend the English language
  • Preferred:

  • A solid understanding of current GLP and/or ISO/CAP/CLIA standards
  • Experience supervising technical personnel
  • Precision is required by law in some states or cities to include a reasonable estimate of the compensation range for this role. This compensation range takes into account the wide range of factors that are considered in making compensation decisions including but not limited to: skill sets, experience and training, licensure and certifications, and other business and organizational needs. The disclosed range estimate has not been adjusted for the applicable geographic differential associated with the location at which the position may be filled. At Precision, it is not typical for an individual to be hired at or near the top of the range for their role and compensation decisions are dependent on the facts and circumstances of each case. This role is also eligible for a discretionary annual bonus, health insurance, retirement savings benefits, life insurance and disability benefits, parental leave, and paid time off for sick leave and vacation, among other benefits.Reasonable estimate of the current range$100,600—$151,000 USD

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    Precision Medicine Group is an Equal Opportunity Employer. Employment decisions are made without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status or other characteristics protected by law.

    If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may contact Precision Medicine Group at myHR@precisionmedicinegrp.com.

    Recruitment Fraud Warning: Please be aware that fraudulent individuals and websites may impersonate Precision Medicine Group or its affiliates and attempt to obtain personal, financial, or banking information through fake job postings or employment offers. Precision Medicine Group will never request payment, banking details, or other sensitive financial information as part of the recruitment process. If you believe you have been targeted by a recruitment scam, we encourage you to report the incident to your local law enforcement authorities, consumer protection agency, or relevant cybercrime reporting organization in your country. Please also notify us at myHR@precisionmedicinegrp.com so we can investigate and take appropriate action.

    Candidates must be legally authorized to work in the country of employment without employer sponsorship.

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