
Scientist 3, Single Cell & Functional Genomics
Required skills
- single-cell CRISPR screens
- Python
- NGS assays
- molecular biology
- high-throughput screens
- cancer cell lines
- primary tissue samples
- genomic data analysis
Nice to have
- epigenomic assays
- epigenomic data analysis
- cancer biology research
Role summary
The Department of Cell and Tissue Genomics is seeking a Scientist 3 with expertise in single-cell and functional genomics to study cancer biology. This role involves performing high-throughput screens, applying single-cell profiling methods to primary tissues, and analyzing genomic data. The successful candidate will collaborate with multidisciplinary teams, publish high-impact research, and identify new research opportunities. A Doctorate degree in a relevant scientific field, hands-on experience with single-cell CRISPR screens, and proficiency in R/Python for data analysis are required. Expertise in NGS assays, molecular biology, and project management are essential. Preferred qualifications include experience in epigenomics and cancer biology research.
The Department of Cell and Tissue Genomics is seeking a creative, rigorous, and motivated Scientist 3 to execute cutting-edge single-cell and functional genomic techniques to study cancer biology. The successful candidate will perform high-throughput screens, deploy new and existing single cell profiling methods, and analyze genomic data to enable the interrogation of molecular mechanisms underlying disease states and identify candidate targets for therapeutic interventions. Working in collaboration with colleagues in the departments of Research Oncology, Translational Medicine, and/or Computational Sciences, this is a hands-on position with both experimental and computational analysis components.
The Opportunity
Perform high-throughput screens in cancer cell lines and models
Develop and apply single cell technologies to profile primary tissue samples.
Analyze and interpret single cell perturbation data and broader genomic data.
Effectively collaborate with teams within the department and across the wider organization.
Communicate results clearly through high-impact scientific publications and presentations.
Contribute to identifying new research opportunities and innovative technology applications.
Who You Are
Education: Doctorate degree in a relevant field, including molecular biology, cancer biology, genetics, immunology, systems biology, developmental biology, biochemistry, and/or biomedical engineering.
Screening Experience: Hands-on experience performing and analyzing single cell CRISPR screens.
Data Analysis: Experience in the analysis of single cell and genomic data using R and/or Python.
NGS Assay Expertise: Strong foundational background in NGS assays and molecular biology techniques.
Professional Skills: Excellent oral and written presentation skills.
Leadership: Ability to manage multiple projects in parallel, collaborate effectively with multidisciplinary teams, and lead research projects.
Scientific Productivity: Sustained record of productivity in the form of publications and patents.
Preferred:
Epigenomics: Experience with epigenomic assays and data analysis.
Disease Expertise: Experience in cancer biology research.
Relocation benefits are available for this posting.
The expected salary range for this position based on the primary location of California is $103,400 - $192,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
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