Role summary
Twist Bioscience is seeking a Technical Project Manager to lead project management, coordination, and implementation for their NGS Services Lab. Reporting to the Director of Technical Sales & Field Application Scientists, this role oversees projects from customer intake to delivery, focusing on scalability, process optimization, and cross-functional alignment in a complex, high-throughput environment. Responsibilities include managing communications with customers, sales, legal, and product management, defining project scope, workflows, costs, and timelines, and ensuring proactive customer expectation management regarding turnaround time and data quality. The role also involves driving continuous improvement and supporting strategic projects, requiring a PhD in a relevant life science field and 5+ years of NGS experience.
Reporting to the Director, Technical Sales & Field Application Scientists, the Technical Project Manager will lead all aspects of project management, coordination, and implementation relative to the NGS Services Lab and related businesses of Twist Bioscience. This role owns execution from customer intake through delivery, driving scalability, process optimization, and cross-functional alignment across a technically complex, high-throughput service environment.
The role manages the full range of communications required to facilitate each project, including customers, sales & field application support, Twist customer service, Twist legal, and the Twist product management group — encompassing non-disclosure agreements, customer quotes, purchase orders, and statements of work.
What You'll Be Doing
Project Leadership for the NGS Service and Applications Lab
Intake, Scoping & Quoting
Serve as the technical and operational lead during project intake, translating customer needs into clearly scoped, executable NGS service programs (DNA, RNA, methylation, long-read)
Own project definition and intake, including: Customer objectives — translate complex customer goals into optimized sequencing strategies and workflows
Scope, assumptions, and constraints
Workflow design and feasibility
Cost, timelines, dependencies, and deliverables
Success criteria aligned to customer outcomes Partner with Sales and FAS to shape opportunities early, including: Defining the right assay or sequencing approach
Identifying risks, tradeoffs, and alternative strategies
Setting realistic expectations with customers Prepare and distribute quotes for NGS service projects; maintain an up-to-date, accessible database of issued quotations, NDAs, purchase orders, and statements of work Post-Intake Execution
Own end-to-end project coordination following intake through final delivery, ensuring continuity between scoping, lab execution, and data delivery
Serve as the central coordination hub across all functions, including: Lab Operations, Bioinformatics, Customer-facing teams (Sales / FAS), and the Customers
Drive regular project syncs with the lab manager (daily/weekly) to track progress vs. timeline, identify risks, and ensure alignment across teams
Serve as the primary point of contact for project updates post-intake
Establish and maintain clear communication cadence, including: status updates, timeline changes, data delivery, and invoicing
Manage customer expectations proactively, especially around: turnaround time (TAT), data quality, and scope changes or technical challenges
Maintain real-time visibility of all active projects, including a transparent, accessible work-in-progress (WIP) list, in coordination with the lab team
Maintain accurate, timely records across all systems to enable up-to-date reporting on quotes issued, orders placed, orders in progress, and orders shipped
Follow applicable regulatory and quality requirements, including ISO 13485, for the service lab Leadership & Continuous Improvement
Provide technical and project leadership to coordinators and cross-functional partners supporting the NGS service lab
Identify and drive process optimization and scalability improvements across the intake-to-delivery lifecycle
Support ad hoc strategic projects as required What You'll Bring to the Team
PhD in Biology, Genetics, Genomics, Molecular Biology, Chemistry, or a related Life Science field
5+ years of relevant experience utilizing Next Generation Sequencing (NGS) technologies, including project or program management experience, with demonstrated experience in a customer-facing role
Expert understanding of NGS workflows (DNA, RNA, methylation, long-read) and the customer workflows the associated service offerings address
Proven track record managing complex, technical projects from intake through delivery that meet customer expectations
Proven ability to influence and lead cross-functional teams, and to work effectively with customers, internal operations, and sales teams
Outstanding leadership, teamwork, and communication skills
Hands-on, high-energy, positive attitude with a can-do approach that gets it done
Highly motivated and results-oriented, with the ability to work under pressure and a strong sense of urgency
Strong organizational skills and excellent problem-solving abilities
Must be able to work outside of regular work hours / a flexible schedule as needed
The base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.San Francisco Bay Area Pay Range$164,000—$203,000 USD
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