Senior Research Associate, High-Throughput RNA Production
Required skills
- high-throughput
- RNA production
- plasmid cloning
- in vitro transcription
- circularization efficiency
- impurity levels
- analytic assays
- DNA synthesis
- scale-up orders
- external vendors
Nice to have
- molecular biology
- cloning
- RNA purification
- HPLC
- column-based purification
- analytic methods
Role summary
Sail Biomedicines is seeking a Senior Research Associate for high-throughput RNA production to advance their programmable circular RNA technology. This role involves end-to-end RNA production, from plasmid cloning to RNA generation and cleanup. Responsibilities include performing high-throughput cloning, RNA generation, analyzing efficiency and impurities, coordinating with vendors, managing inventories, improving workflows with automation engineers, maintaining documentation, and presenting findings. Qualifications include a B.S. in Life Sciences or related field with 2+ years of research experience, or an M.S., with strong organizational and collaborative skills. Preferred qualifications include molecular biology experience, familiarity with HPLC and automated liquid handling systems, and data analysis tool experience.
About Sail
Sail Biomedicines is pioneering the integrative design and deployment of fully programmable medicines to transform patient care. Sail’s platform combines first-in-class programmable circular RNA technology (Endless RNA™ or eRNA), and an industry-leading platform of programmable nanoparticles, utilizing natural components, to unlock comprehensive programming of medicines for the first time. By leveraging cutting-edge eRNA and nanoparticle deployment technology, Sail is also making unparalleled use of AI techniques to identify and design fully programmable medicines that are potent, targeted, versatile, and tunable. Sail was founded by Flagship Pioneering.
The Role
The Senior Research Associate, high-throughput (HTP) RNA production, serves an important role in generating RNAs to advance Sail’s first-in-class programmable circular RNA technology (Endless RNA™ or eRNA). This role will carry out end-to-end process of high-throughput RNA production, from template plasmid cloning to RNA generation and clean up. The successful candidate is organized, attentive to details, a fast learner with a strong sense of responsibility who takes pride in his/her work. The team looks forward to helping you strive in this exciting and fast-paced environment to make a real-world impact on patients’ lives.
Responsibilities
Qualifications
Preferred Qualifications
Salary Range: $75,000 - $95,000
Sail Biomedicines is an Equal Opportunity Employer. Sail does not discriminate based on race, religion, color, sex, gender identity, sexual orientation, age, national origin, veteran status, or any other status protected under federal, state, or local law.
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