Manufacturing, E-commerce, Technology

Senior Principal, ML/AI

Lexington, KYHybridFull TimePrincipalPosted 1 month agoVisa sponsorship available

Is this role right for you?

Upload your resume and get a skill-by-skill breakdown — see exactly where you match, where you're close, and what to highlight. Not a mystery percentage.

Get a tailored resume highlighting what this role needs.

Required skills

2D/3D part understanding
generative AI
advanced machine-learning platforms
foundation models
large-scale vision/3D pipelines
quoting accuracy
defect detection
cost optimization
rapid quoting
generative design

Nice to have

deep generative/3D modeling emphasis

Role summary

Xometry is seeking a Senior Principal, Machine Learning & Artificial Intelligence to lead large, cross-functional ML/AI initiatives. You will define and drive a 18-24 month technical roadmap, balancing innovation with business value. Responsibilities include influencing partner roadmaps, removing roadblocks, identifying opportunities for revenue growth and cost reduction, and staying ahead of industry developments. Key areas of focus include 2D/3D part understanding, generative AI, and advanced ML platforms. The role requires a Master's or PhD, 12+ years of experience in ML/AI/data science, expertise in ML frameworks, MLOps, cloud platforms, and experience with 3D modeling, computer vision, and generative models. Strong collaboration, communication, and mentorship skills are essential.

Xometry (NASDAQ: XMTR) powers the industries of today and tomorrow by connecting the people with big ideas to the manufacturers who can bring them to life. Xometry’s digital marketplace gives manufacturers the critical resources they need to grow their business while also making it easy for buyers at Fortune 1000 companies to tap into global manufacturing capacity.

Xometry is seeking a Senior Principal, Machine Learning & Artificial Intelligence to join our team. You will serve as a technical leader for large, cross-functional ML/AI initiatives that have significant and lasting business impact. You will own and drive an 18- to 24-month technical roadmap that balances innovation with business value delivery. You will work closely with engineering, product, design, manufacturing operations, and business leadership to influence partner roadmaps and resourcing. You will be a respected subject-matter expert, proactively removing roadblocks for teams and tackling problems beyond your immediate scope. You will identify and lead on opportunities to drive revenue growth, cost reduction, efficiency improvement, and competitive differentiation — especially in areas involving 2D/3D part understanding, generative AI, and advanced machine-learning platforms.

How You’ll Contribute:

Serve as the technical leader of multiple large, cross-functional ML/AI solutions with significant, lasting impact across Xometry’s business

Define, and drive the 18-24-month ML/AI technical roadmap - balancing breakthrough innovation (e.g., generative 3D, foundation models, large-scale vision/3D pipelines) with reliable business value delivery (e.g., quoting accuracy, lead-time reduction, defect detection, cost optimization

Influence partner roadmaps across engineering, product, operations, and business teams: align priorities, advise on resourcing, champion ML/AI best practices

Proactively identify and remove roadblocks for teams and projects — whether technical, operational, data-related, or resource constraints

Mentorship of individuals and technical teams

Act as a trusted SME with strong cross-functional partnerships: your insights and guidance will shape ML/AI infrastructure, data, model, infrastructure, and tooling decisions

Play a leadership role in identifying areas of opportunity — e.g., using ML/AI to unlock new revenue streams (e.g., rapid quoting for new manufacturing modalities, generative design for customers), reduce cost (e.g., automated quality inspection), or optimize efficiency (e.g., 3D-geometry classification, defect detection, generating manufacturing ready models)

Address problems adjacent to your sphere of immediate influence: proactively tackle challenges outside direct scope and champion holistic solutions

Stay ahead of industry developments in ML, AI, generative AI, 2D/3D modeling and manufacturing tech; translate insights into the improvement of internal best practices, tooling, frameworks, model governance, data pipelines, and operationalization

Consistently scrutinize existing work, identify opportunities for incremental growth and efficiency optimization - whether in inference latency, model retraining intervals, feature pipelines, cost of compute, or automation of manual tasks

What You'll Bring to Xometry:

Master’s or PhD in Computer Science, Machine Learning, Applied Mathematics, Electrical Engineering or related field (PhD preferred for deep generative/3D modeling emphasis)

12+ years of professional experience in machine learning, artificial intelligence, or data science roles — with several years in senior or principal capacity leading major programs

Demonstrated experience architecting and delivering large scale ML/AI solutions - end-to-end from data ingestion, feature engineering, model training, evaluation, deployment, monitoring & operations

Deep expertise in machine learning frameworks (TensorFlow, PyTorch), data engineering, model infrastructure, MLOps, cloud platforms (AWS, GCP, Azure), and scalable production systems

Experience in 3D modeling / geometry / computer vision / generative models (e.g., point-cloud processing, mesh processing, text23D, image23D, CAD/CAM integration) is highly desirable

Strong exposure to generative AI techniques (large language models, multimodal models, diffusion, GANs) and translating them into business use-cases

Excellent cross-functional collaboration skills: you can partner with product, engineering, ops, manufacturing, design, business leadership and translate technical concepts into business language

Proven ability to influence without direct authority and drive change across organizations

Strong communication and presentation skills; you can articulate technical vision, roadmap, trade-offs and outcomes to senior leadership

Track record of identifying and delivering measurable business impact via ML/AI - e.g., revenue growth, cost savings, improved efficiency

Experience mentoring and guiding teams of ML engineers / data scientists / AI researchers, shaping team culture, practices, and career growth

We also offer a competitive benefits package, including 401(k) match, medical, dental and vision insurance; life and disability insurance; generous paid time off including vacation, sick leave, floating and fixed holidays, maternity and bonding leave; EAP, other wellbeing resources; and much more.

#LI-Hybrid

Xometry is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status.

For US based roles: Xometry participates in E-Verify and after a job offer is accepted, will provide the federal government with your Form I-9 information to confirm that you are authorized to work in the U.S.

Ready to apply?

You'll be redirected to Xometry's application page.

Senior Principal, ML/AI

Is this role right for you?

Required skills

Nice to have

Role summary

Similar roles

See how RiseMe works